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Case Reports
. 1984 Jan;141(1):110-1.
doi: 10.1176/ajp.141.1.110.

Mood-elevating effect of captopril in depressed patients

G S Zubenko, R A Nixon
Case Reports

Mood-elevating effect of captopril in depressed patients

G S Zubenko et al. Am J Psychiatry. 1984 Jan.

Abstract

The use of captopril, an inhibitor of angiotensin-converting enzyme and enkephalinase, was associated with substantial mood elevation in three depressed patients. Substances that may alter neuropeptide synthesis or degradation warrant further investigation as therapeutic agents in certain neuropsychiatric disorders.

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