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Clinical Trial
. 1983 Nov;24(5):713-5.
doi: 10.1128/AAC.24.5.713.

Intranasal interferon as protection against experimental respiratory coronavirus infection in volunteers

P G Higgins, R J Phillpotts, G M Scott, J Wallace, L L Bernhardt, D A Tyrrell
Clinical Trial

Intranasal interferon as protection against experimental respiratory coronavirus infection in volunteers

P G Higgins et al. Antimicrob Agents Chemother. 1983 Nov.

Abstract

In a double-blind, placebo-controlled study, self-administered intranasal human interferon alpha A produced by recombinant DNA technology was given both before and after virus challenge with a respiratory coronavirus. The incidence of colds, the severity of symptoms and signs, and virus replication were all reduced in subjects receiving interferon as compared with those given placebo.

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References

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