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. 1984 Feb;41(1):116-21.
doi: 10.1136/oem.41.1.116.

In vitro macrophage cytotoxicity of five calcium silicates

V Skaug, R Davies, B Gylseth

In vitro macrophage cytotoxicity of five calcium silicates

V Skaug et al. Br J Ind Med. 1984 Feb.

Abstract

Five calcium silicate minerals (two naturally occurring and three synthetic compounds) with defined morphology and chemical composition were compared for their cytotoxic and lysosomal enzyme releasing effects on unstimulated mouse peritoneal macrophages in vitro. One synthetic material, a fibrous tobermorite, was cytotoxic towards the cells, and two naturally occurring wollastonites induced selective release of beta-glucuronidase from the cells.

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