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. 1983 Dec;33(6):567-70.

Macrotiter assay for coronavirus-neutralizing activity in cats using a canine continuous cell line (A-72)

J E Barlough, R H Jacobson, F W Scott
  • PMID: 6319813

Macrotiter assay for coronavirus-neutralizing activity in cats using a canine continuous cell line (A-72)

J E Barlough et al. Lab Anim Sci. 1983 Dec.

Abstract

A heterologous neutralization assay for feline infectious peritonitis virus serology was developed using a single continuous cell line of canine origin, A-72, which is susceptible to cytopathic infection with both transmissible gastroenteritis virus of pigs and canine coronavirus. Of several coronavirus isolates tested, the 1-71 isolate of canine coronavirus demonstrated the most effective neutralization by serum and body fluids of cats with histopathologically confirmed feline infectious peritonitis.

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