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Comparative Study
. 1984 Mar;308(5954):37-43.
doi: 10.1038/308037a0.

The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains

K E Mostov, M Friedlander, G Blobel
Comparative Study

The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains

K E Mostov et al. Nature. 1984 Mar.

Abstract

We have cloned and sequenced cDNA for the receptor that mediates the endocytosis and transcellular transport of IgA and IgM across many glandular epithelia into external secretions. This receptor contains five extracellular domains which are strikingly homologous to each other and to immunoglobulin variable regions.

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