[The use of and value as evidence of polymorphism of phosphoglycolate phosphatase (E.C. 3.1.3.18) in forensic medicine]

Abstract

The paper deals with a description of a modified technique of the electrophoretic demonstration of the phenotypes of phosphoglycolate phosphatase (PGP). The technique yields reproducible results. A total of 369 nonrelated blood donors as well as 138 mother/child pairs were investigated. The blood donors were predominantly of the population of east Westphalia (Münsterland). The following gene-frequencies were calculated: PGP1 0.867, PGP2 0.106, PGP3 0.027. The figures are in good agreement with other German samples. In the mother/child pairs investigated so far there was no irregular segregation. The hypothesis of three alleles on an autosomal locus is thus further confirmed. On the basis of all available family and mother/child data, it is suggested that in the "classical" exclusion method, use of the maximal value is possible. In blood stains that were artificially produced PGP phenotypes were demonstrable up to 6 to 7 weeks.