Joining of V kappa to J kappa gene segments in a retroviral vector introduced into lymphoid cells
- PMID: 6323991
- DOI: 10.1038/308425a0
Joining of V kappa to J kappa gene segments in a retroviral vector introduced into lymphoid cells
Abstract
V kappa to J kappa recombination occurred within a DNA construct introduced into cells in the form of a defective retrovirus. Analysis of one recombinant demonstrated that V kappa-J kappa joining can occur via inversion with a net loss of a few base pairs.
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