Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Mar;3(3):603-10.
doi: 10.1002/j.1460-2075.1984.tb01855.x.

Rearrangements of the transposable mating-type cassettes of fission yeast

D H Beach, A J Klar

Rearrangements of the transposable mating-type cassettes of fission yeast

D H Beach et al. EMBO J. 1984 Mar.

Abstract

The fission yeast, Schizosaccharomyces pombe, switches mating type every few cell divisions. Switching is controlled by the genes of the mating-type locus, which consists of three components, mat1, mat2-P and mat3-M, each separated by approximately 15 kb. Copy transposition of P (Plus) or M (Minus) information from mat2-P or mat3-M into the expression locus mat1 mediates cell type switching. The mating-type locus undergoes events at high frequency (10(-2)-10(-6)) which stabilize one or other mating type. These events are shown to be rearrangements which result in either deletion or insertion of DNA between cassettes.

PubMed Disclaimer

References

    1. J Bacteriol. 1972 May;110(2):667-76 - PubMed
    1. Genetics. 1980 Oct;96(2):315-20 - PubMed
    1. Proc Natl Acad Sci U S A. 1979 Sep;76(9):4539-43 - PubMed
    1. Nature. 1982 Apr 22;296(5859):768-70 - PubMed
    1. Nature. 1977 Mar 10;266(5598):172-4 - PubMed

Publication types