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. 1984 May;309(5965):229-34.
doi: 10.1038/309229a0.

Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

C Wu. Nature. 1984 May.

Abstract

The resistance to exonuclease digestion of two regions of chromatin at the 5' end of heat-shock genes in Drosophila implies they have protein bound to them. The pattern of resistance before and after induction of gene expression suggests that heat-shock genes are activated by the sequential binding of at least two protein factors.

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