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Comparative Study
. 1984 Apr 11;12(7):3127-41.
doi: 10.1093/nar/12.7.3127.

Eight new restriction endonucleases fröm Herpetosiphon giganteus--divergent evolution in a family of enzymes

M Kröger, G Hobom, H Schütte, H Mayer
Free PMC article
Comparative Study

Eight new restriction endonucleases fröm Herpetosiphon giganteus--divergent evolution in a family of enzymes

M Kröger et al. Nucleic Acids Res. .
Free PMC article

Abstract

Characterization of eight restriction endonucleases isolated from five strains of Herpetosiphon giganteus is described. HgiCI from strain Hpg9 recognizes and cleaves the degenerate sequence: GGPyPuCC, producing 5'-hexanucleotide protruding ends. Endonucleases HgiBI, HgiCII and HgiEI are isoschizomers of AvaII; HgiCIII and HgiDII are isoschizomers of SalI; and HgiDI and HgiGI are isoschizomers of AcyI. Based upon their closely related and in part overlapping recognition specificities a close evolutionary relationship is proposed for all known Hgi restriction endonucleases.

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References

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