Isolation and characterization of a stage-specific transforming gene, Tlym-I, from T-cell lymphomas
- PMID: 6326114
- PMCID: PMC345471
- DOI: 10.1073/pnas.81.7.2227
Isolation and characterization of a stage-specific transforming gene, Tlym-I, from T-cell lymphomas
Abstract
A cellular transforming gene detected by transfection of mouse T-cell lymphoma DNA has been isolated by molecular cloning. This gene (designated Tlym-I) is homologous to a small conserved family of sequences present in normal mouse and human DNAs but is not related to any of the previously described viral or cellular transforming genes.
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