Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Jun;50(3):943-6.
doi: 10.1128/JVI.50.3.943-946.1984.

DNA binding properties of a mutant T antigen from the simian virus 40-transformed human cell line simian virus 80

C Gruss, E Baumann, R Knippers

DNA binding properties of a mutant T antigen from the simian virus 40-transformed human cell line simian virus 80

C Gruss et al. J Virol. 1984 Jun.

Abstract

We investigated whether the T antigen of the simian virus 40-transformed human cell line simian virus 80 ( SV80 ) specifically recognizes DNA sequences of its own template, i.e, the viral sequences integrated in the SV80 cellular genome. In vitro DNA binding experiments clearly indicated that, in contrast to wild-type T antigen, SV80 T antigen does not specifically bind to sites on the integrated viral DNA in SV80 cells.

PubMed Disclaimer

References

    1. J Mol Biol. 1975 Nov 5;98(3):503-17 - PubMed
    1. J Mol Biol. 1967 Jun 14;26(2):365-9 - PubMed
    1. Cell. 1978 Jan;13(1):165-79 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1979;43 Pt 2:655-61 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1979;43 Pt 2:709-19 - PubMed

Publication types