Regional localization of two human cellular Kirsten ras genes on chromosomes 6 and 12
- PMID: 6328282
- PMCID: PMC368856
- DOI: 10.1128/mcb.4.5.989-993.1984
Regional localization of two human cellular Kirsten ras genes on chromosomes 6 and 12
Abstract
Human cellular Kirsten ras1 and ras2 genes were localized to chromosomes 6p23 ----q12 and 12p12 .05----pter, respectively, using human-rodent cell hybrids. Thus, the short arms of human chromosomes 11 (encoding lactate dehydrogenase-A and the proto-oncogene c-Ha- ras1 ) and 12 (encoding lactate dehydrogenase B and c-Ki- ras2 ) share at least two pairs of genes that probably evolved from common ancestral genes.
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