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. 1984 Aug;132(2):286-7.
doi: 10.1016/s0022-5347(17)49598-x.

Dissolution of uric acid calculi with systemic alkalization

E D Kursh, M I Resnick

Dissolution of uric acid calculi with systemic alkalization

E D Kursh et al. J Urol. 1984 Aug.

Abstract

We treated 14 patients with uric acid calculi in the renal pelvis and calices (10) or ureter (4) with constant intravenous infusion of a one-sixth molar lactate solution. Dissolution was successful in all but 2 cases. The success of therapy is believed to be related to the sustained urinary alkalization obtained with intravenous infusion compared to the intermittent alkalization that occurs when oral agents are used.

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