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. 1984 Jun 11;12(11):4507-16.
doi: 10.1093/nar/12.11.4507.

A type II restriction endonuclease with an eight nucleotide specificity from Streptomyces fimbriatus

B Q Qiang, I Schildkraut
Free PMC article

A type II restriction endonuclease with an eight nucleotide specificity from Streptomyces fimbriatus

B Q Qiang et al. Nucleic Acids Res. .
Free PMC article

Abstract

A new site-specific endonuclease, Sfi I, has been isolated from Streptomyces fimbriatus . This is the first report of a type II restriction endonuclease whose recognition specificity requires eight nucleotides. Sfi I cleaves the sequence, GGCCNNNN / NGGCC , symmetrically to produce a three base, 3' extension.

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References

    1. Proc Natl Acad Sci U S A. 1977 Aug;74(8):3213-6 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 - PubMed
    1. Science. 1978 May 5;200(4341):494-502 - PubMed
    1. J Mol Biol. 1978 Oct 25;125(2):225-46 - PubMed
    1. J Mol Biol. 1979 Mar 25;129(1):169-72 - PubMed

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