doi: 10.1126/science.6330900.
Cellular transformation by human papillomavirus DNA in vitro
- PMID: 6330900
- DOI: 10.1126/science.6330900
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Cellular transformation by human papillomavirus DNA in vitro
Science.
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Abstract
Molecularly cloned DNA's of human papillomaviruses HPV-5 and HPV-l induced morphological transformation of mouse C127 cells in culture. Single-cell clones of cells transformed by papillomavirus contained multiple persistent episomal copies of the transfected DNA species and were analyzed for growth characteristics indicating malignant potential.
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