Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Sep;141(9):1042-8.
doi: 10.1176/ajp.141.9.1042.

Amish study, IV: Genetic linkage study of pedigrees of bipolar probands

K K Kidd, J A Egeland, L Molthan, D L Pauls, S D Kruger, K H Messner

Amish study, IV: Genetic linkage study of pedigrees of bipolar probands

K K Kidd et al. Am J Psychiatry. 1984 Sep.

Abstract

Genetic linkage studies were conducted on five Old Order Amish bipolar pedigrees in 1979 and 1982, with 94 members tested for color blindness and typed for 42 red blood cell and related markers in 17 antigen systems. Also, 59 individuals in two pedigrees were typed for HLA, Bf, and GLO. Linkage analyses assuming X-linkage and autosomal inheritance of bipolar illness were done with diagnostic schemes ranging from strict bipolar to milder forms of affective disorder. Linkage to affective disorders was not strongly supported for any marker locus. Close linkage to HLA was excluded, with weaker evidence against linkage to GLO.

PubMed Disclaimer

Publication types

LinkOut - more resources