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. 1984 Dec;312(5994):521-4.
doi: 10.1038/312521a0.

Sequence and expression of transcripts of the human T-cell receptor beta-chain genes

Y Yoshikai, D Anatoniou, S P Clark, Y Yanagi, R Sangster, P Van den Elsen, C Terhorst, T W Mak

Sequence and expression of transcripts of the human T-cell receptor beta-chain genes

Y Yoshikai et al. Nature. 1984 Dec.

Abstract

T lymphocytes can produce mRNAs from the first or second constant region of the T-cell antigen receptor beta-chain. A 1.3-kilobase (kb) transcript encoding the mature protein contains V, J and one of the two C region sequences, but does not always contain D sequences. A 1.0-kb mRNA, found mainly in immature T cells, does not contain V sequences and can result from transcription that initiates upstream from an unrearranged J element.

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