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Case Reports
. 1984 Dec;11(6):495-500.
doi: 10.1111/j.1600-0560.1984.tb00409.x.

B-cell markers in malignant B-cell lymphoma with scleroderma-like manifestation

T Van Joost, E Stolz, F B Blog, T H Van der Kwast, V D Vuzevski, J M Van Dongen
Case Reports

B-cell markers in malignant B-cell lymphoma with scleroderma-like manifestation

T Van Joost et al. J Cutan Pathol. 1984 Dec.

Abstract

A case is described of malignant B-cell lymphoma with scleroderma-like manifestation. Using different monoclonals as B-cell markers the tumor appeared to be positive for surface immunoglobulins (SmIg) and for B2-antigen, but negative for intracytoplasmic immunoglobulin (CIg), BA2- and FMC7-antigens. Therefore, the tumor could be determined as a highly differentiated Sm-positive early B-cell type of B-cell lymphoma. In this clinically rare manifestation of cutaneous B-cell lymphoma aspects of the cell morphology and of cellular mediated immunity are briefly discussed.

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