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. 1983 Feb;153(2):1079-82.
doi: 10.1128/jb.153.2.1079-1082.1983.

Escherichia coli xth mutants are hypersensitive to hydrogen peroxide

B Demple, J Halbrook, S Linn

Escherichia coli xth mutants are hypersensitive to hydrogen peroxide

B Demple et al. J Bacteriol. 1983 Feb.

Abstract

Escherichia coli mutants lacking exonuclease III (xthA) are exceptionally sensitive to hydrogen peroxide. They are killed by H2O2 at 20 times the rate of wild-type bacteria and at 3 to 4 times the rate of recA cells. This is the first clear phenotypic sensitivity reported for xth- E. coli and should aid in clarifying peroxide-induced lethality and the in vivo role of exonuclease III.

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References

    1. J Bacteriol. 1982 Jul;151(1):351-7 - PubMed
    1. J Biol Chem. 1952 Mar;195(1):133-40 - PubMed
    1. J Biol Chem. 1982 Oct 10;257(19):11750-4 - PubMed
    1. Nucleic Acids Res. 1982 Jun 25;10(12):3781-9 - PubMed
    1. Genetics. 1966 Jun;53(6):1137-50 - PubMed

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