Malaria renders mice susceptible to mosquito feeding when gametocytes are most infective

Abstract

Mice infected with Plasmodium berghei, P. chabaudi, or P. yoelii became lethargic and ceased to display normal antimosquito behavior. Periods of reduced defensiveness corresponded with maximum mosquito engorgement and with periods of maximum gametocyte infectivity to mosquitoes. Increased feeding success of mosquitoes during periods of peak gametocyte infectivity may be important to the natural maintenance of these malaria parasites.