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. 1983 Feb;80(4):1092-5.
doi: 10.1073/pnas.80.4.1092.

Vibrio cholerae hemagglutinin/lectin/protease hydrolyzes fibronectin and ovomucin: F.M. Burnet revisited

R A Finkelstein, M Boesman-Finkelstein, P Holt

Vibrio cholerae hemagglutinin/lectin/protease hydrolyzes fibronectin and ovomucin: F.M. Burnet revisited

R A Finkelstein et al. Proc Natl Acad Sci U S A. 1983 Feb.

Abstract

Cholera vibrios produce a single polymeric protein that (i) causes hemagglutination; (ii) appears to participate in their attachment to gut epithelium; (iii) may mediate their detachment from gut epithelium; and (iv) is a protease that hydrolyzes fibronectin and mucin, cleaves lactoferrin, and nicks the A subunit of the choleragen-related heat-labile enterotoxin of Escherichia coli.

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