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Comparative Study
. 1983 Oct;80(19):5890-4.
doi: 10.1073/pnas.80.19.5890.

Z-DNA immunoreactivity in fixed metaphase chromosomes of primates

E Viegas-Péquignot, C Derbin, B Malfoy, E Taillandier, M Leng, B Dutrillaux
Comparative Study

Z-DNA immunoreactivity in fixed metaphase chromosomes of primates

E Viegas-Péquignot et al. Proc Natl Acad Sci U S A. 1983 Oct.

Abstract

Antibodies against Z-DNA bind to fixed metaphase chromosomes of man and Cebus albifrons (Platyrrhini, Primate). By indirect immunofluorescence and indirect immunoperoxidase techniques, a heavy staining is detected in some segments of chromosomes of C. albifrons. These segments correspond to R-band-positive heterochromatin, which has a high G + C-base content. Euchromatin of human and Cebus chromosomes show a weak and heterogeneous staining that consistently reproduces an R- and T-banding pattern in both species. Because chromosome homologies previously were demonstrated between these distantly related species by chromosome banding, our results suggest that Z-DNA has been conserved during the course of primate evolution.

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References

    1. Biochimie. 1982 Jun;64(6):443-50 - PubMed
    1. Nature. 1982 Sep 23;299(5881):312-6 - PubMed
    1. Exp Cell Res. 1982 Oct;141(2):508-13 - PubMed
    1. Nature. 1982 Dec 9;300(5892):545-6 - PubMed
    1. Biochemistry. 1982 Oct 26;21(22):5463-7 - PubMed

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