Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Jan;118(1):226-8.

Conformational integrity of myoglobin after immunization with Freund's adjuvant

J A Smith, J G Hurrell, S J Leach
  • PMID: 63516

Conformational integrity of myoglobin after immunization with Freund's adjuvant

J A Smith et al. J Immunol. 1977 Jan.

Abstract

The use of Freund's complete adjuvant for immunizing goats with myoglobin produces mainly antibodies directed against antigenic determinants present in the native protein. Only about 9% of the total antibodies produced are directed toward determinants not expressed in tha native molecule. This shows that neither emulsification nor the subsequent in vivo events leading up to the immune response appreciably perturb the conformation of the protein surface.

PubMed Disclaimer

LinkOut - more resources