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Comparative Study
. 1983 Sep;32(5):943-6.
doi: 10.4269/ajtmh.1983.32.943.

An enzyme-linked immunosorbent assay (ELISA) for field diagnosis of visceral leishmaniasis

M Ho, J Leeuwenburg, G Mbugua, A Wamachi, A Voller
Comparative Study

An enzyme-linked immunosorbent assay (ELISA) for field diagnosis of visceral leishmaniasis

M Ho et al. Am J Trop Med Hyg. 1983 Sep.

Abstract

A simplified enzyme-linked immunosorbent assay (ELISA) was evaluated as a diagnostic test for visceral leishmaniasis in the field on 222 individuals with splenomegaly and 110 controls. The test was shown to have a sensitivity of 98.4% and specificity of 100% when compared with parasite identification by splenic aspiration. The data indicate that the ELISA is an accurate, safe, and economical alternative to splenic aspiration for the diagnosis of visceral leishmaniasis.

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