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Comparative Study
. 1983 Aug;364(8):1053-7.
doi: 10.1515/bchm2.1983.364.2.1053.

The occurrence of N-acetyl- and N-glycoloylneuraminic acid in Trypanosoma cruzi

Comparative Study

The occurrence of N-acetyl- and N-glycoloylneuraminic acid in Trypanosoma cruzi

R Schauer et al. Hoppe Seylers Z Physiol Chem. 1983 Aug.

Abstract

Different strain of Trypanosoma cruzi were analysed to have 65--105 micrograms of sialic acids per 10(10) cells. By thin-layer chromatography, and in part by gas liquid chromatography and gas-liquid chromatography-mass spectrometry, all strains were found to contain N-acetyl- and N-glycoloylneuraminic acid in various ratios. After incubation of the parasites with either [3H]acetate or N-acetyl-[3H]mannosamine, no radioactivity was found in the sialic acids, thus leading to the suggestion that the parasites are unable to synthesize sialic acids from their precursors.

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