The occurrence of N-acetyl- and N-glycoloylneuraminic acid in Trypanosoma cruzi
- PMID: 6354906
- DOI: 10.1515/bchm2.1983.364.2.1053
The occurrence of N-acetyl- and N-glycoloylneuraminic acid in Trypanosoma cruzi
Abstract
Different strain of Trypanosoma cruzi were analysed to have 65--105 micrograms of sialic acids per 10(10) cells. By thin-layer chromatography, and in part by gas liquid chromatography and gas-liquid chromatography-mass spectrometry, all strains were found to contain N-acetyl- and N-glycoloylneuraminic acid in various ratios. After incubation of the parasites with either [3H]acetate or N-acetyl-[3H]mannosamine, no radioactivity was found in the sialic acids, thus leading to the suggestion that the parasites are unable to synthesize sialic acids from their precursors.
Similar articles
-
Natural occurrence and preparation of O-acylated 2,3-unsaturated sialic acids.Carbohydr Res. 1987 Nov 1;168(2):199-209. doi: 10.1016/0008-6215(87)80026-5. Carbohydr Res. 1987. PMID: 3427580
-
A detailed study of the periodate oxidation of sialic acids in glycoproteins.Glycoconj J. 1989;6(1):35-44. doi: 10.1007/BF01047888. Glycoconj J. 1989. PMID: 2562505
-
Identification of new sialic acids derived from glycoprotein of bovine submandibular gland.Eur J Biochem. 1983 Jul 15;134(1):139-43. doi: 10.1111/j.1432-1033.1983.tb07542.x. Eur J Biochem. 1983. PMID: 6861756
-
Characterization of sialic acids.Methods Enzymol. 1978;50:64-89. doi: 10.1016/0076-6879(78)50008-6. Methods Enzymol. 1978. PMID: 207950 Review. No abstract available.
-
Entry of Trypanosoma cruzi into eukaryotic cells.Infect Agents Dis. 1992 Jun;1(3):136-45. Infect Agents Dis. 1992. PMID: 1365537 Review.
Cited by
-
Insights into the evolution of sialic acid catabolism among bacteria.BMC Evol Biol. 2009 May 26;9:118. doi: 10.1186/1471-2148-9-118. BMC Evol Biol. 2009. PMID: 19470179 Free PMC article.
-
Identification of the gene(s) coding for the trans-sialidase of Trypanosoma cruzi.EMBO J. 1992 May;11(5):1705-10. doi: 10.1002/j.1460-2075.1992.tb05221.x. EMBO J. 1992. PMID: 1374711 Free PMC article.
-
Trypanosoma Cruzi Genome: Organization, Multi-Gene Families, Transcription, and Biological Implications.Genes (Basel). 2020 Oct 14;11(10):1196. doi: 10.3390/genes11101196. Genes (Basel). 2020. PMID: 33066599 Free PMC article. Review.
-
Identification of N-acetylneuraminic acid and its 9-O-acetylated derivative on the cell surface of Cryptococcus neoformans: influence on fungal phagocytosis.Infect Immun. 1997 Dec;65(12):4937-42. doi: 10.1128/iai.65.12.4937-4942.1997. Infect Immun. 1997. PMID: 9393779 Free PMC article.
-
Sialoglycans in protozoal diseases: their detection, modes of acquisition and emerging biological roles.Glycoconj J. 2004;20(3):199-206. doi: 10.1023/B:GLYC.0000024251.30100.08. Glycoconj J. 2004. PMID: 15090733 Review.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Other Literature Sources