Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1983 Nov;16(5):561-4.
doi: 10.1111/j.1365-2125.1983.tb02217.x.

A comparison of a combination of penbutolol and frusemide with the two compounds individually in the treatment of hypertension

D R Chadha, J J Houtzagers
Clinical Trial

A comparison of a combination of penbutolol and frusemide with the two compounds individually in the treatment of hypertension

D R Chadha et al. Br J Clin Pharmacol. 1983 Nov.

Abstract

Forty-one patients completed a randomized, double-blind, between-group comparison of a combination of penbutolol and frusemide, with penbutolol alone, and frusemide alone in the management of mild to moderate essential hypertension. The results suggest that the combination caused a superior reduction in systolic and diastolic pressure compared with penbutolol and a superior reduction in systolic blood pressure compared with frusemide.

PubMed Disclaimer

References

    1. J Clin Pharmacol. 1979 Aug-Sep;19(8-9 Pt 1):476-86 - PubMed
    1. S Afr Med J. 1981 Jun 13;59(25):891-3 - PubMed
    1. Am Heart J. 1981 Oct;102(4):734-40 - PubMed
    1. Br J Clin Pharmacol. 1979 Apr;7(4):404-5 - PubMed
    1. Eur J Clin Pharmacol. 1981;21(2):93-6 - PubMed