Monoclonal antibodies specific for differentiation antigens of human myelomonocytic cells

Abstract

Several monoclonal antibodies specific for human cells of the myelomonocytic lineage at discrete stages of differentiation have been described. In this review I briefly summarize the results obtained with these reagents and discuss their possible use for the study of cell lineage and functional activities of normal peripheral blood leukocytes, for the analysis of myelomonocytic cell differentiation in vivo and in vitro and for the antigenic phenotyping of leukemia cells.