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. 1983;306(5945):751-6.
doi: 10.1038/306751a0.

Isolate-specific S-antigen of Plasmodium falciparum contains a repeated sequence of eleven amino acids

Isolate-specific S-antigen of Plasmodium falciparum contains a repeated sequence of eleven amino acids

R L Coppel et al. Nature. 1983.

Abstract

Antibodies raised against a Plasmodium falciparum protein expressed in Escherichia coli reacted with a 220,000-molecular weight antigen of mature blood-stage parasites. The protein resembles the sporozoite surface antigen being composed of tandem repeats of 11 amino acids. However, it is isolate-specific and the encoding gene is not detectable in strains that do not express the protein.

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