[Our experience with the clinical trial of postinor--an oral hormonal preparation for postcoital contraception]
- PMID: 6362451
[Our experience with the clinical trial of postinor--an oral hormonal preparation for postcoital contraception]
Abstract
PIP: Postcoital contraception aims at the avoidance of unwanted pregnancy in women who have a regimen of rare or accidental sexual contacts. For the 1st time in Bulgaria, the authors examined clinically an oral postcoital preparation, Postinor, which originated in Hungary. Each tablet contains 0.75 mcg of d-norgestrel. The observation included 49 volunteers, ages 19-38, with proven fertility. The preparations were given during the course of 150 menstrual cycles. 1 women became pregnant as a result of improper dosage/multiple contacts during incomplete hormonal protection. There were 3 cases of bleeding (6.1%) and 1 required estrogen correction. The authors found that the best administration regimen was 1 tablet, with the exception of 2 tablets/week. The authors suggest that Postinor could be successfully combined with the rhythm method of Ogion-Knaus. They recommend it for daily contraceptive practice. (author's modified)