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. 1984 Feb;98(2):678-84.
doi: 10.1083/jcb.98.2.678.

Bud formation by the yeast Saccharomyces cerevisiae is directly dependent on "start"

R A Singer, D P Bedard, G C Johnston

Bud formation by the yeast Saccharomyces cerevisiae is directly dependent on "start"

R A Singer et al. J Cell Biol. 1984 Feb.

Abstract

Cells of the yeast Saccharomyces cerevisiae, which bear a cdc4 gene mutation, arrest early in the cell cycle but continue to produce buds in a periodic fashion. We show here that this periodic bud formation by cells already arrested at the CDC4 step is inhibited if the cell cycle regulatory step "start" is also specifically blocked by mutation or by the presence of the yeast mating pheromone alpha-factor. Thus, the characteristic periodic bud formation by cdc4 mutant cells requires the continued ability to perform start. This finding raises questions concerning the nature of start; these issues are discussed.

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References

    1. J Cell Physiol. 1978 Jun;95(3):393-405 - PubMed
    1. J Mol Biol. 1971 Jul 14;59(1):183-94 - PubMed
    1. J Bacteriol. 1977 Nov;132(2):723-30 - PubMed
    1. J Mol Biol. 1974 Apr 15;84(3):445-61 - PubMed
    1. J Bacteriol. 1970 Dec;104(3):1280-5 - PubMed

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