Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Jan;307(5948):241-5.
doi: 10.1038/307241a0.

Transcriptional interference in avian retroviruses--implications for the promoter insertion model of leukaemogenesis

B R Cullen, P T Lomedico, G Ju

Transcriptional interference in avian retroviruses--implications for the promoter insertion model of leukaemogenesis

B R Cullen et al. Nature. 1984 Jan.

Abstract

The downstream (3') long terminal repeat (LTR) of an avian retroviral provirus is unable to act as an efficient promoter of transcription when a transcriptionally active upstream (5') LTR is present. This transcriptional interference may explain the observation that only deleted proviruses have been observed inserted adjacent to c-myc in avian leukosis virus induced lymphomas of chickens.

PubMed Disclaimer

LinkOut - more resources