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. 1984 Feb;4(2):383-5.
doi: 10.1128/mcb.4.2.383-385.1984.

Chromosomal assignment of the murine gene encoding the transformation-related protein p53

V Rotter, D Wolf, D Pravtcheva, F H Ruddle

Chromosomal assignment of the murine gene encoding the transformation-related protein p53

V Rotter et al. Mol Cell Biol. 1984 Feb.

Abstract

p53 is a transformation-related protein that is encoded by the cellular genome and is synthesized at elevated levels in a wide range of different cell line types and in primary tumors of various species. By using several independently established anti-p53 monoclonal antibodies, it was possible to distinguish between p53 of mouse origin and p53 of Chinese hamster origin. By analysis of a series of mouse X Chinese hamster hybrid cell lines containing various mouse chromosomes, we mapped the p53 gene product to mouse chromosome 11.

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