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Review
. 1984 Jan-Feb;93(1 Pt 1):28-33.
doi: 10.1177/000348948409300107.

Etiopathogenesis of otosclerosis: a hypothesis

Review

Etiopathogenesis of otosclerosis: a hypothesis

T J Yoo. Ann Otol Rhinol Laryngol. 1984 Jan-Feb.

Abstract

It is hypothesized that otosclerosis is an autoimmune disease in response to native type II collagens of cartilage rests associated with globular ossei in the endochondral layer of the otic capsule. To support this hypothesis animal experimental data and human antibody data are shown.

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