Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1984 Feb 29;56(4):385-92.
doi: 10.1007/BF00155683.

Short-term and long-term timolol maleate effects on corneal sensitivity

D Spinelli, F Vigasio, P Montanari
Clinical Trial

Short-term and long-term timolol maleate effects on corneal sensitivity

D Spinelli et al. Doc Ophthalmol. .

Abstract

The authors present data concerning the effect of timolol maleate on corneal sensitivity investigated with the Cochet-Bonnet aesthesiometer and with cotton wool wisps. Among 30 subjects with open-angle glaucoma, 15 subjects underwent a short-term trial with timolol maleate 0.50% in one eye, while 15 served in a long-term trial with timolol maleate 0.50% or 0.25% in both eyes. A light reduction in corneal sensitivity, which did not reach statistical significance, was found during timolol treatment. After discussing the possible explanations of this side effect, the authors advise monitoring this parameter during the therapy.

PubMed Disclaimer

References

    1. Am J Ophthalmol. 1979 Oct;88(4):739-43 - PubMed
    1. Invest Ophthalmol Vis Sci. 1977 Mar;16(3):240-2 - PubMed
    1. Med J Aust. 1980 Jan 12;1(1):34 - PubMed
    1. Arch Ophthalmol. 1979 Apr;97(4):656-8 - PubMed
    1. Br J Ophthalmol. 1976 May;60(5):312-23 - PubMed

Publication types