Review
doi: 10.1007/BF00286587.
Human oncogenes
- PMID: 6370829
- DOI: 10.1007/BF00286587
Item in Clipboard
Review
Human oncogenes
Hum Genet.
1984.
Abstract
The information published on human oncogenes up to the fall of 1983 is reviewed. Retroviral oncogenes, proto-oncogenes, and cellular transforming genes are compared. Transforming genes derived from the ras gene family are described in detail. The different mechanisms of activation of proto-oncogenes are summarized. Finally, the concerted or sequential action of cellular transforming genes in the multi-step process of carcinogenesis is discussed.
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