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Review
. 1984;66(2-3):132-42.
doi: 10.1007/BF00286587.

Human oncogenes

K Willecke, R Schäfer
Review

Human oncogenes

K Willecke et al. Hum Genet. 1984.

Abstract

The information published on human oncogenes up to the fall of 1983 is reviewed. Retroviral oncogenes, proto-oncogenes, and cellular transforming genes are compared. Transforming genes derived from the ras gene family are described in detail. The different mechanisms of activation of proto-oncogenes are summarized. Finally, the concerted or sequential action of cellular transforming genes in the multi-step process of carcinogenesis is discussed.

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References

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