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. 1984 Jun 15;40(6):582-3.
doi: 10.1007/BF01982343.

Reversal of pyrithiamine-induced growth inhibition of Saccharomyces cerevisiae by oxythiamine

Reversal of pyrithiamine-induced growth inhibition of Saccharomyces cerevisiae by oxythiamine

A Iwashima et al. Experientia. .

Abstract

Oxythiamine reversed the growth inhibition of Saccharomyces cerevisiae caused by pyrithiamine, although oxythiamine alone inhibited yeast cell growth. This phenomenon was explained by thiamine production from these 2 thiamine antagonists which was demonstrated using cell suspensions and the crude extract of S. cerevisiae.

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