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. 1984 Jun;16(3):709-12.

Deterioration in glucose metabolism in pancreatic transplant recipients after conversion from azathioprine to cyclosporine

R Gunnarsson, G Klintmalm, G Lundgren, G Tydén, H Wilczek, J Ostman, C G Groth
  • PMID: 6375038

Deterioration in glucose metabolism in pancreatic transplant recipients after conversion from azathioprine to cyclosporine

R Gunnarsson et al. Transplant Proc. 1984 Jun.

Abstract

Six recipients of combined pancreas and kidney transplants displayed a deterioration in glucose tolerance when the immunosuppressive therapy was changed from azathioprine-prednisolone to cyclosporine-prednisolone. Because at the same time the plasma C-peptide level increased it seems that insulin resistance, rather than reduced insulin secretion, caused the impairment in glucose tolerance. The condition was found to be reversible.

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