Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Jul;107(3):355-65.
doi: 10.1093/genetics/107.3.355.

Coincident gene conversion during mitosis in saccharomyces

J E Golin, M S Esposito

Coincident gene conversion during mitosis in saccharomyces

J E Golin et al. Genetics. 1984 Jul.

Abstract

During mitosis, gene conversion events at the TRP5 locus on chromosome VII are coupled with conversion events at LEU1, a locus 18 cM away, 1200 times more frequently than would be expected for two independent acts of recombination. Such coincident conversion events that occur over relatively long distances could be due to several mechanisms. We discuss these possibilities and describe an experiment that indicates that a portion of coincident events is due to extensive heteroduplexes. The phenomenon of coincident gene conversion is discussed in relation to our earlier evidence that spontaneous recombination between homologues occurs prereplicationally in mitosis.

PubMed Disclaimer

References

    1. Genetics. 1963 Mar;48:321-8 - PubMed
    1. Genetics. 1968 Jun;59(2):191-210 - PubMed
    1. Proc Natl Acad Sci U S A. 1975 Jan;72(1):358-61 - PubMed
    1. Mol Gen Genet. 1973 Apr 12;122(2):137-48 - PubMed
    1. Genetics. 1943 Nov;28(6):491-511 - PubMed

Publication types