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. 1984 Apr;28(1):123-5.
doi: 10.1016/0378-1119(84)90095-7.

Correlation of DNA adenine methylase activity with spontaneous mutability in Escherichia coli K-12

M G Marinus, A Poteete, J A Arraj

Correlation of DNA adenine methylase activity with spontaneous mutability in Escherichia coli K-12

M G Marinus et al. Gene. 1984 Apr.

Abstract

Using a multicopy plasmid in which the tac promoter has been placed in front of the dam gene of Escherichia coli K-12, we show that levels of DNA adenine methylase activity are correlated with the spontaneous mutation frequency.

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