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Case Reports
. 1984 Jul;38(1):34-7.
doi: 10.1097/00007890-198407000-00009.

Cyclosporin-associated central nervous system toxicity after allogeneic bone marrow transplantation

K Atkinson, J Biggs, P Darveniza, J Boland, A Concannon, A Dodds
Case Reports

Cyclosporin-associated central nervous system toxicity after allogeneic bone marrow transplantation

K Atkinson et al. Transplantation. 1984 Jul.

Abstract

Five of 64 recipients of HLA-identical sibling marrow allografts who were given cyclosporin (CSP) to minimize graft-versus-host disease posttransplant had a serious neurological illness thought to be due to CSP. Characteristic clinical features included a motor spinal cord syndrome, a cerebellar-like syndrome, and mental confusion. All five recovered when the CSP dose was reduced or the drug was stopped.

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