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. 1984 Jul;37(7):787-9.
doi: 10.1136/jcp.37.7.787.

Fibronectin as an opsonic regulator of monocyte phagocytosis

A W Simpson, B J Boughton

Fibronectin as an opsonic regulator of monocyte phagocytosis

A W Simpson et al. J Clin Pathol. 1984 Jul.

Abstract

Experiments using human monocytes and the yeast Saccharomyces cerevisiae have shown that fibronectin is a major plasma opsonin. Further studies have shown that fibronectin promotes the ingestion as well as the adherence of micro-organisms. These observations are independent of the non-physiological concentrations of heparin used in other assay systems.

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