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. 1984 Sep;29(3):271-9.
doi: 10.1016/0378-1119(84)90056-8.

The nucleotide sequence of the yeast ARG4 gene

I R Beacham, B W Schweitzer, H M Warrick, J Carbon

The nucleotide sequence of the yeast ARG4 gene

I R Beacham et al. Gene. 1984 Sep.

Abstract

The complete nucleotide sequence of a 2296-bp DNA fragment containing the yeast (Saccharomyces cerevisiae) ARG4 gene has been determined. This gene specifies the synthesis of the arginine biosynthetic enzyme, argininosuccinate lyase (EC 4.3.2.1). The sequence contains one major open reading frame of 463 codons, giving a calculated Mr of 52 010 for the protein, in good agreement with the experimentally determined value of 53 000. The sequence upstream from the ARG4 gene shares structural features in common with other yeast genes subject to general amino acid control.

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