Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983 Jan 29;286(6362):333-6.
doi: 10.1136/bmj.286.6362.333.

Positron emission tomography in venous ulceration and liposclerosis: study of regional tissue function

N F Hopkins, T J Spinks, C G Rhodes, A S Ranicar, C W Jamieson

Positron emission tomography in venous ulceration and liposclerosis: study of regional tissue function

N F Hopkins et al. Br Med J (Clin Res Ed). .

Abstract

Oxygen-15 administered by continuous inhalation and emission computed tomography were used to study regional tissue oxygen utilisation and blood flow in the limbs of 11 patients with venous ulceration and five patients with liposclerosis due to venous insufficiency. The results showed increased blood flow and appreciably reduced fractional oxygen extraction in the diseased tissues. These findings indicated a local, functional shunting of blood through the abnormal microcirculation of the skin and subcutaneous tissues. This may be an important factor in the aetiology of the skin changes seen in patients with calf muscle pump failure.

PubMed Disclaimer

References

    1. J Nucl Med. 1978 Jun;19(6):635-47 - PubMed
    1. J Nucl Med. 1975 Mar;16(3):210-24 - PubMed
    1. Br Med Bull. 1980 Sep;36(3):231-6 - PubMed
    1. Arch Surg. 1960 Aug;81:299-310 - PubMed
    1. Br J Radiol. 1976 Apr;49(580):339-43 - PubMed

Substances

LinkOut - more resources