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. 1983 Feb 19;286(6365):590-2.
doi: 10.1136/bmj.286.6365.590.

Maturity onset diabetes of the young is not linked to the insulin gene

J I Bell, J S Wainscoat, J M Old, C Chlouverakis, H Keen, R C Turner, D J Weatherall

Maturity onset diabetes of the young is not linked to the insulin gene

J I Bell et al. Br Med J (Clin Res Ed). .

Abstract

Maturity onset diabetes of the young is inherited as an autosomal dominant condition. Two families with the disease were studied to determine whether the inheritance of this type of diabetes was linked to the insulin gene. A cloned insulin gene probe was hybridised to DNA from the family members and the insulin gene on each chromosome identified by a different fragment length polymorphism. The results showed no linkage between the insulin gene and the inheritance of maturity onset diabetes of the young.

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