doi: 10.1007/BF00284747.
[Intraarterial bleomycin therapy on squamous cell carcinomas of the oral cavity. Clinico-pathological investigations (author's transl)]
[Article in
German]
- PMID: 64041
- DOI: 10.1007/BF00284747
Item in Clipboard
[Intraarterial bleomycin therapy on squamous cell carcinomas of the oral cavity. Clinico-pathological investigations (author's transl)]
[Article in
German]
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol.
.
Abstract
The mode of action of bleomycin after intraarterial perfusion in 53 patients with advanced squamous cell carcinoma of the oral cavity is reported on the basis of clinical results and pathologico-anatomic findings. In 29 out of 32 cases not previously treated a clinically complete remission could be achieved by primary chemotherapy. In 8 cases these findings were histomorphologically confirmed and 7 patients have shown a persistant remission for 9 to 61 months. The chances of success are much less favorable in the treatment of recurrences. No clinical advantages were observed when combining bleomycin with other chemotherapeutics.
Similar articles
-
The effects of intra-arterial bleomycin therapy on squamous cell carcinoma of the oral cavity. Biopsy and autopsy examinations.J Maxillofac Surg. 1975 Dec;3(4):217-30. doi: 10.1016/s0301-0503(75)80048-8. J Maxillofac Surg. 1975. PMID: 54400
-
[Technique and clinical assessment of the intra-arterial chemotherapy of squamous cell carcinoma (author's transl)].Arch Geschwulstforsch. 1982;52(2):113-6. Arch Geschwulstforsch. 1982. PMID: 6179496 German. No abstract available.
-
[Combination therapy for advanced oral squamous cell carcinoma with radiation and bleomycin. I. Primary regression and early mucosal reaction (author's transl)].Newsl Int Coll Dent India Sect. 1980 Jan 25;40(1):36-42. Newsl Int Coll Dent India Sect. 1980. PMID: 6154281 Japanese. No abstract available.
-
[Clinical effects of NK 631 in malignant tumors of the oral cavity (author's transl)].Jpn J Antibiot. 1979 Jan;32(1):138-48. Jpn J Antibiot. 1979. PMID: 84884 Japanese. No abstract available.
-
Chemotherapy for oral and maxillofacial tumors: an update.Oral Maxillofac Surg Clin North Am. 2014 May;26(2):163-9. doi: 10.1016/j.coms.2014.01.004. Oral Maxillofac Surg Clin North Am. 2014. PMID: 24794265 Review.
Cited by
-
Vascular lesions following perfusion with bleomycin. Electron-microscopic observations.Virchows Arch A Pathol Anat Histol. 1976 Dec 27;372(3):227-36. doi: 10.1007/BF00433281. Virchows Arch A Pathol Anat Histol. 1976. PMID: 65049
-
Pharmacokinetics of intra-arterial tumour therapy. An experimental study.Arch Otorhinolaryngol. 1984;239(2):153-61. doi: 10.1007/BF00463556. Arch Otorhinolaryngol. 1984. PMID: 6712530
-
Giant cell stromal reaction in squamous cell carcinomata. Electronmicroscopic and ultrahistochemical observations on the genesis and functional activity of multinucleated giant cells in bleomycin-induced tumor regression.Virchows Arch A Pathol Anat Histol. 1977 Oct 7;375(4):263-80. doi: 10.1007/BF00427058. Virchows Arch A Pathol Anat Histol. 1977. PMID: 72448