Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983;105(3):299-302.
doi: 10.1007/BF00395762.

Preputial tumors induced by intragastric intubations of 7,12-dimethylbenz(a)anthracene in gonadectomized female and male rats

Preputial tumors induced by intragastric intubations of 7,12-dimethylbenz(a)anthracene in gonadectomized female and male rats

H Yoshida. J Cancer Res Clin Oncol. 1983.

Abstract

A series of administrations of 7,12-dimethylbenz(a)anthracene given at biweekly intervals by gastric intubation to gonadectomized rats of the Sprague-Dawley strain elicited a considerable number of preputial tumors. The tumors commonly consisted of solid and cystic parts with a wide variety of histologic features and were classified as adenomas, carcinomas, and malignant mixed tumors.

PubMed Disclaimer

References

    1. Beahrs, O., Woolner LB, Kirklin JW, Devine KD (1957) Carcinomatous transformation of mixed tumors of the parotid gland. Arch Surg 75:605–614 - PubMed
    1. Gawienowski AM, Orsulak PJ, Stacewicz-Sapuntzakis M, Joseph BM (1975) Presence of sex pheromone in preputial glands of male rats. J Endorcrinol 67:283–288 - PubMed
    1. Grigor MR, Platt RD, Synder F (1972) Acylation of cholesterol by microsomal enzymes from mouse preputial gland tumors. Arch Biochem Biophys 150:371–375 - PubMed
    1. Hiraga K, Fujii T (1977) Tumors of the preputial gland in rats. Gann 68:369–370 - PubMed
    1. Huggins C, Grand L, Brillantes FP (1961) Mammary cancer induced by a single feeding of polynuclear hydrocarbons, and its suppression. Nature 189:204–207 - PubMed

Substances

LinkOut - more resources