Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1983 Mar;25(3):393-6.
doi: 10.1016/0090-6980(83)90042-4.

Soybean lipoxygenase inhibition by nonsteroidal antiinflammatory drugs

J C Sircar, C F Schwender, E A Johnson
Comparative Study

Soybean lipoxygenase inhibition by nonsteroidal antiinflammatory drugs

J C Sircar et al. Prostaglandins. 1983 Mar.

Abstract

Eighteen known nonsteroidal antiinflammatory drugs (NSAID) were tested for their action against soybean lipoxygenase (E.C.1.13.11.12) using linoleic acid as substrate. It was found that the best inhibitors of lipoxygenase were naproxen, BW 755C, indomethacin and isoxicam. Drugs with intermediate potency were meclofenamic acid, phenylbutazone and benoxaprofen. Other drugs such as ibuprofen and zomepirac were only weakly active in the test.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources