A maximum likelihood estimate of the sex ratio of mutation rates in haemophilia A
- PMID: 6411604
- DOI: 10.1007/BF00327115
A maximum likelihood estimate of the sex ratio of mutation rates in haemophilia A
Abstract
Carrier detection tests were carried out on 21 mothers of isolated cases of severe Haemophilia A, according to WHO recommendations. A maximum likelihood estimate of the male to female mutation ratio of 9.6 (95% confidence limits 2.2-41.5) was obtained.
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